Neuromuscular disease, respiratory failure and cor pulmonale.

Severe pectus excavatum associated with cor pulmonale and chronic respiratory acidosis in a young woman.

Pectus excavatum has never been reported to cause hypercapnic respiratory failure. In this report, we describe the first such case in a young woman with severe pectus excavatum who presented with chronic respiratory acidosis, pulmonary hypertension, and chronic cor pulmonale. An extensive diagnostic workup failed to uncover any other cause of respiratory acidosis, which led us to conclude that ...

Chronic cor pulmonale.

The term “cor pulmonale” is still very popular in the medical literature, but its definition varies and there is presently no consensual definition. Forty years ago an expert committee of the World Health Organization defined cor pulmonale as “hypertrophy of the right ventricle resulting from diseases affecting the function and/or structure of the lungs . . .”. This pathological definition is i...

Rare Cause of Type 2 Respiratory Failure: Arnold Chiari Malformation.

S y r i n g o m y e l i a i . e . I m p a i r e d neuromuscular transmission is a rare cause (0.01%) of type 2 respiratory failure. Here i am discussing a case who presented with hypercapnic respiratory failure and on evolution found to be afflicted with extensive syrinx involving cervical spinal cord. A prediabetic 45 yrs old lady presented in our casualty with complaints of cough with expecto...

The circulatory effects of acute respiratory failure: with special reference to acute cor pulmonale.

The Circulatory Effects of Acute

Respiratory failure may be defined as the inability to maintain normal oxygen and carbon dioxide tensions in the arterial blood under normal atmospheric conditions. This condition will lead to serious functional disturbances of the cardiovascular system if hypoxia and hypercapnoea become severe. In addition, parenchymatous disease of the lungs, disorders affecting the mechanics of the thoracic ...